Plate 06

Guttate Psoriasis

Also called: Eruptive psoriasis

Psoriasis
Illustration © Roxana Barin Click to enlarge

General information

  • Acute variant of psoriasis characterized by the sudden eruption of numerous small, erythematous, scaly “drop-like” papules.
  • Most commonly occurs in children, adolescents, and young adults.
  • Frequently triggered by a streptococcal infection, particularly pharyngitis caused by group A Streptococcus pyogenes.
  • The eruption classically develops 1–3 weeks after an upper respiratory tract infection.
  • Other infections may also act as triggers.
  • May represent the first manifestation of psoriasis or occur in a patient with a personal or family history of psoriasis.
  • May resolve spontaneously within weeks to months, although some patients subsequently develop chronic plaque psoriasis.

Symptoms / presentation

  • Acute, rapidly disseminating eruption of numerous small lesions.
  • Frequently preceded by a recent sore throat or respiratory infection.
  • Lesions may be asymptomatic or associated with variable pruritus.
  • Individual lesions are considerably smaller and more numerous than typical plaque psoriasis lesions.
  • Recurrences may occur following subsequent streptococcal infections.

Clinical exam

  • Multiple erythematous or salmon-pink papules, typically measuring a few millimeters to approximately 1 cm.
  • Well-demarcated, round or oval, “drop-like” lesions.
  • Covered by fine white or silvery scales, which may be subtle early in the eruption.
  • Numerous lesions may produce the appearance of a widespread exanthem.
  • Auspitz sign may occur: pinpoint bleeding after removal of scale, although this finding is neither required nor specific for the diagnosis.
  • Variable pruritus.

Distribution

  • Trunk +++
  • Proximal upper and lower extremities
  • Scalp may be involved
  • Face is usually less prominently affected
  • Palms and soles are generally spared
  • Distribution is often bilateral and symmetric

Dermoscopy

  • Regularly distributed dotted vessels on an erythematous background.
  • Diffuse white scaling.
  • Relatively uniform and symmetric vascular distribution.
  • These findings can help distinguish psoriasis from other papulosquamous disorders.

Diagnosis

  • Primarily a clinical diagnosis based on characteristic morphology and distribution.
  • Assess for a recent streptococcal infection, particularly when pharyngeal symptoms are present.
  • Rapid antigen testing or throat culture if active streptococcal pharyngitis is suspected.
  • ASO or anti-DNase B titers may occasionally help document a recent streptococcal infection when clinically relevant.
  • Skin biopsy is rarely required but may be considered for an atypical presentation or diagnostic uncertainty.

Differential diagnosis

  • Pityriasis rosea
  • Morbilliform drug eruption
  • Secondary syphilis
  • Pityriasis lichenoides
  • Generalized lichen planus
  • Multifocal dermatophytosis
  • Other infectious or drug-related exanthems depending on the clinical context

Treatment plan

  • Mild disease may resolve spontaneously and require primarily symptomatic treatment.
  • Emollients to reduce dryness and scaling.
  • Topical corticosteroids of appropriate potency may be used for symptomatic or inflammatory lesions.
  • Avoid prolonged application of superpotent topical corticosteroids over large body surface areas.
  • Widespread disease: narrowband UVB (NB-UVB/TL01) phototherapy is commonly preferred when phototherapy is indicated.
  • A confirmed active streptococcal infection should be treated according to standard recommendations for streptococcal pharyngitis.
  • Antibiotics are not an established treatment for the psoriatic eruption itself once an active streptococcal infection is no longer present.
  • Systemic psoriasis therapy is rarely necessary for an isolated episode but may be considered for persistent, severe disease or progression to chronic psoriasis.

References

  1. DermNet — Guttate psoriasis.
  2. American Academy of Dermatology (AAD) — Psoriasis clinical guidelines.
  3. UpToDate — Guttate psoriasis.
  4. Bolognia JL, Schaffer JV, Cerroni L. Dermatology. Elsevier.