Plate 06
Guttate Psoriasis
Also called: Eruptive psoriasis
PsoriasisGeneral information
- Acute variant of psoriasis characterized by the sudden eruption of numerous small, erythematous, scaly “drop-like” papules.
- Most commonly occurs in children, adolescents, and young adults.
- Frequently triggered by a streptococcal infection, particularly pharyngitis caused by group A Streptococcus pyogenes.
- The eruption classically develops 1–3 weeks after an upper respiratory tract infection.
- Other infections may also act as triggers.
- May represent the first manifestation of psoriasis or occur in a patient with a personal or family history of psoriasis.
- May resolve spontaneously within weeks to months, although some patients subsequently develop chronic plaque psoriasis.
Symptoms / presentation
- Acute, rapidly disseminating eruption of numerous small lesions.
- Frequently preceded by a recent sore throat or respiratory infection.
- Lesions may be asymptomatic or associated with variable pruritus.
- Individual lesions are considerably smaller and more numerous than typical plaque psoriasis lesions.
- Recurrences may occur following subsequent streptococcal infections.
Clinical exam
- Multiple erythematous or salmon-pink papules, typically measuring a few millimeters to approximately 1 cm.
- Well-demarcated, round or oval, “drop-like” lesions.
- Covered by fine white or silvery scales, which may be subtle early in the eruption.
- Numerous lesions may produce the appearance of a widespread exanthem.
- Auspitz sign may occur: pinpoint bleeding after removal of scale, although this finding is neither required nor specific for the diagnosis.
- Variable pruritus.
Distribution
- Trunk +++
- Proximal upper and lower extremities
- Scalp may be involved
- Face is usually less prominently affected
- Palms and soles are generally spared
- Distribution is often bilateral and symmetric
Dermoscopy
- Regularly distributed dotted vessels on an erythematous background.
- Diffuse white scaling.
- Relatively uniform and symmetric vascular distribution.
- These findings can help distinguish psoriasis from other papulosquamous disorders.
Diagnosis
- Primarily a clinical diagnosis based on characteristic morphology and distribution.
- Assess for a recent streptococcal infection, particularly when pharyngeal symptoms are present.
- Rapid antigen testing or throat culture if active streptococcal pharyngitis is suspected.
- ASO or anti-DNase B titers may occasionally help document a recent streptococcal infection when clinically relevant.
- Skin biopsy is rarely required but may be considered for an atypical presentation or diagnostic uncertainty.
Differential diagnosis
- Pityriasis rosea
- Morbilliform drug eruption
- Secondary syphilis
- Pityriasis lichenoides
- Generalized lichen planus
- Multifocal dermatophytosis
- Other infectious or drug-related exanthems depending on the clinical context
Treatment plan
- Mild disease may resolve spontaneously and require primarily symptomatic treatment.
- Emollients to reduce dryness and scaling.
- Topical corticosteroids of appropriate potency may be used for symptomatic or inflammatory lesions.
- Avoid prolonged application of superpotent topical corticosteroids over large body surface areas.
- Widespread disease: narrowband UVB (NB-UVB/TL01) phototherapy is commonly preferred when phototherapy is indicated.
- A confirmed active streptococcal infection should be treated according to standard recommendations for streptococcal pharyngitis.
- Antibiotics are not an established treatment for the psoriatic eruption itself once an active streptococcal infection is no longer present.
- Systemic psoriasis therapy is rarely necessary for an isolated episode but may be considered for persistent, severe disease or progression to chronic psoriasis.
References
- DermNet — Guttate psoriasis.
- American Academy of Dermatology (AAD) — Psoriasis clinical guidelines.
- UpToDate — Guttate psoriasis.
- Bolognia JL, Schaffer JV, Cerroni L. Dermatology. Elsevier.